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The Ohio State University Comprehensive Cancer Center
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Research Programs


Molecular Carcinogenesis and Chemoprevention

The global objective of this program is to elucidate molecular and cellular mechanisms underlying carcinogenesis and develop novel strategies for cancer prevention through chemoprevention and nutrition. To achieve this goal, researchers: 1) characterize molecular and cellular changes induced by chemical, physical, hormonal and infectious agents that contribute to neoplastic transformation and multi-stage carcinogenesis in experimental models and humans; 2) develop and characterize novel agents for cancer chemoprevention and gauge their safety, efficacy and mechanisms using in vitro and preclinical models; 3) identify dietary and nutritional components that enhance or inhibit the carcinogenic cascade; and 4) implement cancer-prevention studies in humans with emphasis on those who are at greater risk due to exposure to cancer-promoting agents, genetic predisposition or the presence of premalignant lesions. The program’s translational research component has grown to include more than 2,000 participants at Ohio State involved in chemoprevention or nutrition studies under the direction of program members.

Download 2008-09 Seminar Schedule

Program Leaders

     

Steven K. Clinton, M.D., Ph.D.

Professor
Internal Medicine
A437A Starling Loving
320 W. 10th Avenue Columbus,OH. 432101240

 

o

(614) 293-2886

f

(614) 293-7525
steven.clinton@osumc.edu
 

Program Members

     

Robert W. Brueggemeier, Ph.D.

Professor/ Dean
Pharmacy
217 Parks Hall
500 w. 12th Ave. Columbus,OH. 43210-1291

 

o

(614) 292-5711

f

(614) 292-2435
brueggemeier.1@osu.edu
 
     

Bruce C. Casto, Dr. Sc.

Sr Research Scientist
College of Public Health
1146 CHRI
300 W. 10th Avenue Columbus,OH. 43210

 

o

(614) 366-3735

f

(614) 293-7710
casto.44@osu.edu
 
     

Ching-Shih Chen, Ph.D.

Professor
Pharmacy
Parks Hall, Room 336
500 West 12th Avenue Columbus,OH. 43210

 

o

(614) 688-4008

f

(614) 688-8556
chen.844@osu.edu
 
     

Tong Chen, M.D.

Research Asst. Professor
Internal Medicine
1325
2001 Polaris Pkwy Columbus,OH. 43240

 

o

(614) 293-2691

f

tong.chen@osumc.edu
 
     

Robert W. Curley, Jr., Ph.D.

Professor
Pharmacy
606 Riffe Building
496 W. 12th Ave. Columbus,OH. 43210

 

o

(614) 292-7628

f

(614) 292-2435
curley.1@osu.edu
 
     

Steven M. D'Ambrosio, Ph.D.

Professor Emeritus
Radiology
BRT 714
460 W. 12th Ave Columbus,OH. 43210

 

o

(614) 292-9035

f

(614) 292-9102
dambrosio.1@osu.edu
 
     

Robert A. DiSilvestro, Ph.D.

Professor
Human Nutrition
345 Campbell Hall
1787 Neil Avenue Columbus,OH. 432101295

 

o

(614) 292-6848

f

(614) 292-8880
disilvestro.1@osu.edu
 
     

Andrea I. Doseff, Ph.D.

Asst Professor
Internal Medicine
201 Davis Heart & Lung
473 W 12th Ave Columbus,OH. 43210

 

o

(614) 292-9507

f

(614) 292-7778
andrea.doseff@osumc.edu
 
     

Mark L. Failla, Ph.D.

Assoc Dean for Research
Human Nutrition
325 Campbell Hall
1787 Neil Avenue Columbus,OH. 43210

 

o

(614) 292-4485

f

(614) 292-8880
failla.3@osu.edu
 
     

William B. Farrar, M.D.

Professor
Surgery
N924 Doan Hall
410 W. 10th Avenue Columbus,OH. 43210

 

o

(614) 293-8890

f

(614) 293-3465
william.farrar@osumc.edu
 
     

H. L. Grimes, Ph.D.

Assoc Professor
Pediatrics
Division of Immunobiology - MLC 7038
3333 Burnet Ave, Room 5564 Cincinnati,OH. 452293039

 

o

(513) 636-6089

f

(513) 636-5355
lee.grimes@cchmc.org
 
     

A. Douglas Kinghorn, Ph.D., D.Sc.

Professor
Pharmacy
446 Parks Hall
500 W 12th Ave Columbus,OH. 43210

 

o

(614) 247-8094

f

(614) 247-8117
kinghorn.4@osu.edu
 
     

Junan Li, Ph.D.

Research Asst. Professor
College of Public Health
Rm 3160 Graves Hall
333 W. 10th Ave. Columbus,OH. 43210

 

o

(614) 292-4066

f

(614) 292-4053
li.225@osu.edu
 
     

Pui-kai Li, Ph.D.

Assc Professor
Pharmacy
328 Parks
500 W. 12th Avenue Columbus,OH. 43210

 

o

(614) 688-0253

f

(614) 292-2435
li.27@osu.edu
 
     

Young C. Lin, D.V.M., Ph.D.

Professor
Veterinary Biosciences
Rm 450
1900 Coffey Road Columbus,OH. 432101092

 

o

(614) 292-9706

f

(614) 292-2077
lin.15@osu.edu
 
     

Richard R. Love, M.D.

Professor
Internal Medicine
B402 Starling Loving
320 W 10th Ave Columbus,OH. 43210

 

o

(614) 293-2948

f

richard.love@osumc.edu
 
     

Susan R. Mallery, D.D.S., Ph.D.

Professor
Oral Pathology
2191B Postle Hall
305 W. 12th Avenue Columbus,OH. 43210

 

o

(614) 292-5892

f

(614) 292-9384
mallery.1@osu.edu
 
     

Amir Mortazavi, M.D.

Asst Professor
Internal Medicine
A441 Starling-Loving Hall
320 W 10th Ave Columbus,OH. 43210

 

o

(614) 293-2886

f

(614) 293-7525
amir.mortazavi@osumc.edu
 
     

Peter Muscarella, M.D.

Assoc Professor
Surgery
N711 Doan Hall
410 West 10th Avenue Columbus,OH. 43210

 

o

(614) 293-5815

f

(614) 293-4030
pete.muscarella@osumc.edu
 
     

Tatiana M. Oberyszyn, Ph.D.

Assoc Professor
Pathology
129 Hamilton Hall
1645 Neil Avenue Columbus,OH. 43210

 

o

(614) 293-9803

f

(614) 293-9805
tatiana.oberyszyn@osumc.edu
 
     

Qishen Pang, Ph.D.

Asst Professor
Pediatrics
3333 Burnet Ave Cincinnati,OH. 45229

 

o

(513) 636-1152

f

(513) 636-3768
Qishen.pang@cchmc.org
 
     

Dehua Pei, Ph.D.

Professor
Chemistry
1118 Newman-Wolfrom Laboratory
100 W. 18th Street Columbus,OH. 43210

 

o

(614) 688-4068

f

(614) 292-1532
pei.3@osu.edu
 
     

Michael A. Pereira, Ph.D.

Professor Emeritus
Internal Medicine
1148B James Cancer Hospital
300 W.10th Avenue Columbus,OH. 43210

 

o

(614) 293-6864

f

(614) 293-4072
michael.pereira@osumc.edu
 
     

Thomas J. Rosol, D.V.M., Ph.D.

Professor
Veterinary Biosciences
Goss Lab
1925 Coffey Road Columbus,OH. 43210

 

o

(614) 292-4265

f

(614) 292-6473
rosol.1@osu.edu
 
     

Steven J. Schwartz, Ph.D.

Professor
Food Science & Technology
235 Parker
2015 Fyffe Court Columbus,OH. 43210

 

o

(614) 292-2934

f

(614) 292-4233
schwartz.177@osu.edu
 
     

Chandan K. Sen, M.D.

Professor
Surgery
513 DHLRI
473 W. 12th Avenue Columbus,OH. 43210

 

o

(614) 293-7399

f

chandan.sen@osumc.edu
 
     

Gary D. Stoner, Ph.D.

Professor Emeritus
Internal Medicine
OSU Innovation Center
2001 Polaris Parkway Columbus,OH. 43240

 

o

(614) 293-3268

f

(614) 293-2690
gary.stoner@osumc.edu
 
     

Yael Vodovotz, Ph.D.

Assoc Professor
Food Science & Technology
227
2015 Fyffe Ct Columbus,OH. 43210

 

o

(614) 247-7696

f

vodovotz.1@osu.edu
 
     

Qianben Wang, Ph.D.

Asst Professor
Molecular and Cellular Biochemistry
888 BRT
460 W 12th Ave. Columbus,OH. 43210

 

o

(614) 247-1609

f

qianben.wang@osumc.edu
 
     

Altaf A. Wani, Ph.D.

Professor
Radiology
OSU Innovation Center
2001 Polaris Parkway Columbus,OH. 43240

 

o

(614) 293-0847

f

(614) 293-0802
wani.2@osu.edu
 
     

Christopher M. Weghorst, Ph.D.

Assoc Professor
College of Public Health
M110 Starling Loving Hall
320 W. 10th Avenue Columbus,OH. 43210

 

o

(614) 293-8441

f

(614) 293-7710
weghorst.2@osu.edu
 
     

Traci Wilgus, Ph.D.

Asst Professor
Pathology
129 Hamilton Hall
1645 Neil Avenue Columbus,OH. 43210

 

o

(614) 366-8526

f

(614) 366-9389
traci.wilgus@osumc.edu
 
     

Lisa D. Yee, M.D.

Assoc Professor
Surgery
N924 Doan Hall
410 W. 10th Avenue Columbus,OH. 43210

 

o

(614) 293-6654

f

(614) 293-3465
lisa.yee@osumc.edu
 
     

Yi Zheng, Ph.D.

Professor
Pediatrics
Experimental Hematology
3333 Burnet Ave Cincinnati,OH. 45229

 

o

(513) 636-0595

f

(513) 636-3768
Yi.zheng@chmcc.org
 
     

Ouliana Ziouzenkova, Ph.D.

Asst Professor
Human Nutrition
331A Campbell Hall
1787 Neil Ave. Columbus,OH. 43210

 

o

(614) 292-5034

f

(614) 292-8880
ziouzenkova.1@osu.edu
 
     

Xianghong Zou, Ph.D.

Asst Professor
Pathology
140 Hamilton Hall
1645 Neil Avenue Columbus,OH. 43210

 

o

(614) 688-8424

f

xianghong.zou@osumc.edu