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OSUCCC
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Michael C. Ostrowski, Ph.D.
Professor / Chair
College of Biological Sciences
Molecular and Cellular Biochemistry
810 Biomedical Research Tower
460 West 12th Avenue Columbus,OH. 43210
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(614) 688-3824 |
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(614) 688-8727 |
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Programs
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| A major initiative within the MBCG Program is the $8.7 million P01 grant from the National Cancer Institute entitled "Genetic Analysis of the Tumor Microenvironment" led by Dr. Ostrowski. Click here to learn more about this grant > Program Project Grant. |
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Current Publications
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Circulation 119(4): 538-46, 2009
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Ambient air pollution exaggerates adipose inflammation and insulin resistance in a mouse model of diet-induced obesity.
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Sun Q, Yue P, Deiuliis JA, Lumeng CN, Kampfrath T, Mikolaj MB, Cai Y, Ostrowski MC, Lu B, Parthasarathy S, Brook RD, Moffatt-Bruce SD, Chen LC, Rajagopalan S
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Cancer Res 69(17): 6759-64, 2009
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Genomic alterations in tumor stroma.
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Eng C, Leone G, Orloff MS, Ostrowski MC
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461(7267): 1084-91, 2009
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Pten in stromal fibroblasts suppresses mammary epithelial tumours.
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Trimboli AJ, Cantemir-Stone CZ, Li F, Wallace JA, Merchant A, Creasap N, Thompson JC, Caserta E, Wang H, Chong JL, Naidu S, Wei G, Sharma SM, Stephens JA, Fernandez SA, Gurcan MN, Weinstein MB, Barsky SH, Yee L, Rosol TJ, Stromberg PC, Robinson ML, Pepin F, Hallett M, Park M, Ostrowski MC, Leone G
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PLoS One 4(1): e4208, 2009
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The PtdIns 3-kinase/Akt pathway regulates macrophage-mediated ADCC against B cell lymphoma.
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Joshi T, Ganesan LP, Cheney C, Ostrowski MC, Muthusamy N, Byrd JC, Tridandapani S
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Dev Dyn 237(10): 2926-35, 2008
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Analysis of the IKKbeta/NF-kappaB signaling pathway during embryonic angiogenesis.
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Hou Y, Li F, Karin M, Ostrowski MC
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Cancer Res 68(24): 10257-66, 2008
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Breast cancer-associated fibroblasts confer AKT1-mediated epigenetic silencing of Cystatin M in epithelial cells.
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Lin HJ, Zuo T, Lin CH, Kuo CT, Liyanarachchi S, Sun S, Shen R, Deatherage DE, Potter D, Asamoto L, Lin S, Yan PS, Cheng AL, Ostrowski MC, Huang TH
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PLoS Genet 3(9): 1757-69, 2008
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CpG island methylation in a mouse model of lymphoma is driven by the genetic configuration of tumor cells.
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Opavsky R, Wang SH, Trikha P, Raval A, Huang Y, Wu YZ, Rodriguez B, Keller B, Liyanarachchi S, Wei G, Davuluri RV, Weinstein M, Felsher D, Ostrowski M, Leone G, Plass C
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Cancer Res 68(3): 937-45, 2008
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Direct evidence for epithelial-mesenchymal transitions in breast cancer.
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Trimboli AJ, Fukino K, de BA, Wei G, Shen L, Tanner SM, Creasap N, Rosol TJ, Robinson ML, Eng C, Ostrowski MC, Leone G
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J Clin Invest 118(11): 3775-89, 2008
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NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism.
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Aliprantis AO, Ueki Y, Sulyanto R, Park A, Sigrist KS, Sharma SM, Ostrowski MC, Olsen BR, Glimcher LH
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J Cell Physiol 215(3): 636-44, 2008
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PU.1 and NFATc1 mediate osteoclastic induction of the mouse beta3 integrin promoter.
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Crotti TN, Sharma SM, Fleming JD, Flannery MR, Ostrowski MC, Goldring SR, McHugh KP
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Med Image Anal 13(1): 156-66, 2008
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Tensor classification of N-point correlation function features for histology tissue segmentation.
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Mosaliganti K, Janoos F, Irfanoglu O, Ridgway R, Machiraju R, Huang K, Saltz J, Leone G, Ostrowski M
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J Virol 81(17): 9357-67, 2008
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The early protective thymus-independent antibody response to foot-and-mouth disease virus is mediated by splenic CD9+ B lymphocytes.
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Ostrowski M, Vermeulen M, Zabal O, Zamorano PI, Sadir AM, Geffner JR, Lopez OJ
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J Immunol 180(10): 6733-42, 2008
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The Ewing sarcoma protein (EWS) binds directly to the proximal elements of the macrophage-specific promoter of the CSF-1 receptor (csf1r) gene.
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Hume DA, Sasmono T, Himes SR, Sharma SM, Bronisz A, Constantin M, Ostrowski MC, Ross IL
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Nature 451(7174): 73-5, 2008
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Trisomy represses Apc(Min)-mediated tumours in mouse models of Down's syndrome.
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Sussan TE, Yang A, Li F, Ostrowski MC, Reeves RH
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