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OSUCCC
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Werner Tjarks, Ph.D.
Assoc Professor
College of Pharmacy
Pharmacy - Medicinal Chemistry & Pharmacognosy
421 Parks Hall
500 W. 12th Avenue Columbus,OH. 43210
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(614) 292-7624 |
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(614) 292-2435 |
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Programs
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Current Publications
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Appl Radiat Isot 67(7-8 Suppl): S328-31, 2009
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Boron neutron capture therapy of EGFR or EGFRvIII positive gliomas using either boronated monoclonal antibodies or epidermal growth factor as molecular targeting agents.
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Yang W, Barth RF, Wu G, Tjarks W, Binns P, Riley K
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J Chem Inf Model 49(6): 1581-9, 2009
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Carborane clusters in computational drug design: a comparative docking evaluation using AutoDock, FlexX, Glide, and Surflex.
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Tiwari R, Mahasenan K, Pavlovicz R, Li C, Tjarks W
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J Neurooncol in press: , 2009
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Convection enhanced delivery of boronated EGF as a molecular targeting agent for neutron capture therapy of brain tumors.
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Yang W, Barth RF, Wu G, Huo T, Tjarks W, Ciesielski M, Fenstermaker RA, Ross BD, Wikstrand CJ, Riley KJ, Binns PJ
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Chem Commun (Camb) (47): 4978-91, 2008
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Carboranyl thymidine analogues for neutron capture therapy.
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Tjarks W, Tiwari R, Byun Y, Narayanasamy S, Barth RF
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Clin Cancer Res 14(3): 883-91, 2008
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Molecular targeting and treatment of composite EGFR and EGFRvIII-positive gliomas using boronated monoclonal antibodies.
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Yang W, Wu G, Barth RF, Swindall MR, Bandyopadhyaya AK, Tjarks W, Tordoff K, Moeschberger M, Sferra TJ, Binns PJ, Riley KJ, Ciesielski MJ, Fenstermaker RA, Wikstrand CJ
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J Microsc 229(Pt 1): 92-103, 2008
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Quantitative subcellular imaging of boron compounds in individual mitotic and interphase human glioblastoma cells with imaging secondary ion mass spectrometry (SIMS).
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Chandra S, Tjarks W, Lorey DR, Barth RF, Lorey DR 2nd
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Nucleosides Nucleotides Nucleic Acids 27(3): 244-60, 2008
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Synthesis and biological evaluation of inhibitors of thymidine monophosphate kinase from Bacillus anthracis.
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Byun Y, Vogel SR, Phipps AJ, Carnrot C, Eriksson S, Tiwari R, Tjarks W
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Proc Natl Acad Sci U S A 105(45): 17493-7, 2008
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Thymidine kinase 1 as a molecular target for boron neutron capture therapy of brain tumors.
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Barth RF, Yang W, Wu G, Swindall M, Byun Y, Narayanasamy S, Tjarks W, Tordoff K, Moeschberger ML, Eriksson S, Binns PJ, Riley KJ
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