About MASR
Microarray is a powerful high throughput technology that can monitor thousands of gene mRNAs by transcriptional profiling in a single experiment. To accelerate cancer research, the OSUCCC has sponsored and supported the microarray core facility as a shared resource in the center. In general, the aim of the facility is to provide a centralized resource of high throughput microarray technologies to the OSUCCC cancer research community.
The MicroArray Shared Resource (MASR) for the OSU Comprehensive Cancer Center (OSUCCC) is located in a dedicated laboratory of over 1300 sq ft on the 4th floor of the Wiseman Hall at 410 West 12th Avenue. The MASR has been established and well equipped with
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Affymetrix GeneChip System including two GeneChip Hyb-Station Oven 320/640, Two Affy. Fluidics Station 450 and One Affy. GeneChip Scanner 3000; and
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The system for in-house custom microarray including GeneMachine OminiGrid 100 Arrayer; Tecan TeMo Liquid Handling Workstation and four Tecan HS4800 Hybridization Stations; two Axon 4000B and 4200A Microarray Scanners, two MJ Tetrad thermocycler and PE 9700 PCR Machines.
The Services provided at MASR are:
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mRNA: Genome-wide and targeted mRNA transcriptional profiling on Affymetrix and Custom expression platforms
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microRNA: Genome-wide human/mouse microRNA expression profiling on custom microarray
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SNP: Genome-wide and targeted SNP genotyping on Affymetrix and Custom platforms.
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CGH: microarray-based comparative genomic hybridization (CGH) for genomic gain/loss detection on SpectroGenomics (CGH) BAC arrays; microRNA-specific genomic CGH detection on custom oligo array.
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RNA quality: To provide quantitative measurement of RNA integrity to improve the quality and reliability of expression analysis.
